What is Waldenstrom's Macroglobulinemia?
Waldenstrom's Macroglobulinemia is a type of non-Hodgkin
lymphoma that produces large amounts of an abnormal
protein. This extra protein causes most of the symptoms
of the disease, including excessive bleeding, problems
with vision, and nervous system problems. According
to the American Cancer Society, it is estimated that
about 1,500 people in the United States are diagnosed
as having Waldenstrom Macroglobulinemia each year.
Risk Factors
There are no known ways to prevent Waldenstrom Macroglobulinemia
as the confirmed risk factors, such as aging, cannot
be changed or controlled. It has been determined that
the disease is rare in people under age 50 and more
prevalent in white males than in any other group.
Common Symptoms
Consult a medical professional if you experience these
symptoms:
- Enlarged lymph nodes that can be felt
- Abdominal swelling
- Unexplained weight loss
- Fever
- Profuse sweating, particularly at night
- Severe itchiness
- Fatigue
- Confusion, dizziness, or stroke-like symptoms
- Abnormal bleeding
- Problems with vision
- Weakness
- Shortness of breath
- Frequent or recurring infections
Common Treatment Options
If a person diagnosed with Waldenstrom's Macroglobulinemia
does not have any symptoms and/or does not have anemia
(a shortage of red blood cells), there is no need for
immediate treatment. Once a decision has been made to
start treatment, options considered may include chemotherapy,
use of Interferon or monoclonal antibodies or treatment
with thalidomide.
Chemotherapy
Chemotherapy is a type of treatment that uses drugs
to stop the growth of cancer cells, either by killing
the cells or by stopping the cells from dividing. Chemotherapy
drugs can be taken orally or by injection depending
on the type and stage of the cancer and the drug protocol
your doctor has prescribed. It is important to discuss
your treatment protocol with your treatment team so
you are aware of any possible side effects.
